Five-Year Follow-Up Data from the U.S. Clinical Trial for Sientra’s U.S. Food and Drug Administration-Approved Silimed® Brand Round and Shaped Implants with High-Strength Silicone Gel

BACKGROUND:: In March of 2012, the U.S. Food and Drug Administration approved Sientra’s application for premarket approval for its Silimed brand silicone gel implants, based on data from the largest silicone gel breast implant study to date. This was the first approval for shaped silicone gel breast implants. This article presents the results of Sientra’s

Individualized weight management: what can be learned from nutrigenomics and nutrigenetics?

The rise in the prevalence of obesity observed over the past decades is taken by many as an indication of the predominance of environmental factors (the so-called obesogenic environment) over genetic factors in explaining why obesity has reached epidemic proportions. While a changing environment favoring increased food intake and decreased physical activity levels has clearly

From cardiovascular prevention to anti-aging medicine: influence on telomere and cell aging

The most important cardiovascular risk factors (hypercholesterolemia , hypertension, diabetes, chronic stress, physical inactivity, smoking, adipositas) were evaluated in the second half of the last century using placebo controlled trials. The mechanismen of action was not fully understood or remained unclear. In some studies not only the risk of atherosclerosis was reduced but life expectancy